{"id":18743,"date":"2026-06-05T17:31:32","date_gmt":"2026-06-05T08:31:32","guid":{"rendered":"https:\/\/www.nsg.gr.jp\/blog\/?p=18743"},"modified":"2026-06-05T17:31:32","modified_gmt":"2026-06-05T08:31:32","slug":"nuhw_ancient-dental-calculus_202606","status":"publish","type":"post","link":"https:\/\/www.nsg.gr.jp\/blog\/nuhw_ancient-dental-calculus_202606\/","title":{"rendered":"\u6b6f\u77f3DNA\u304b\u3089\u8aad\u307f\u89e3\u304f\u3001\u904e\u53bb\u306e\u65e5\u672c\u4eba\u3068\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u95a2\u308f\u308a"},"content":{"rendered":"<p><span style=\"font-size: 12pt;\">\u6771\u90a6\u5927\u5b66\u3001\u6771\u4eac\u5927\u5b66\u3001\u8fb2\u696d\u30fb\u98df\u54c1\u7523\u696d\u6280\u8853\u7dcf\u5408\u7814\u7a76\u6a5f\u69cb\u3001\u56fd\u969b\u533b\u7642\u798f\u7949\u5927\u5b66\u3001\u8056\u30de\u30ea\u30a2\u30f3\u30ca\u533b\u79d1\u5927\u5b66\u3001\u4e5d\u5dde\u5927\u5b66\u3001\u56fd\u7acb\u79d1\u5b66\u535a\u7269\u9928\u3001\u65e5\u672c\u5927\u5b66\u3001\u571f\u4e95\u30f6\u6d5c\u907a\u8de1\u30fb\u4eba\u985e\u5b66\u30df\u30e5\u30fc\u30b8\u30a2\u30e0\u3001\u65b0\u6f5f\u533b\u7642\u798f\u7949\u5927\u5b66\u3001\u938c\u5009\u5973\u5b50\u5927\u5b66\u3001\u6c96\u7e04\u770c\u7acb\u57cb\u8535\u6587\u5316\u8ca1\u30bb\u30f3\u30bf\u30fc\u3001\u65b0\u6f5f\u5927\u5b66\u3001\u6771\u4eac\u79d1\u5b66\u5927\u5b66\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6c5f\u6238\u6642\u4ee3\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u65e5\u672c\u5217\u5cf6\u306e\u53e4\u4eba\u9aa8\u306e\u6b6f\u77f3\u304b\u3089\u5fae\u751f\u7269DNA\u3092\u89e3\u6790\u3057\u3001\u904e\u53bb\u306e\u53e3\u8154\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\uff08\u6ce81\uff09\u306e\u7279\u5fb4\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u53e4\u4eba\u9aa8\u7531\u6765\u306e\u6b6f\u77f3\u306b\u542b\u307e\u308c\u308b\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u69cb\u6210\u306f\u73fe\u4ee3\u6b6f\u77f3\u3068\u306f\u7570\u306a\u308a\u3001\u5730\u57df\u5dee\u3084\u6642\u4ee3\u306b\u3088\u308b\u4e00\u90e8\u306e\u7d30\u83cc\u7cfb\u7d71\u306e\u9055\u3044\u304c\u3042\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u6b6f\u5468\u75c5\u95a2\u9023\u53e4\u7d30<em>Methanobrevibacter oralis<\/em>\uff08\u4ee5\u4e0b\u3001<em>M. oralis<\/em>\uff09\uff08\u6ce82\uff09\u306e\u7cfb\u7d71\u89e3\u6790\u3067\u306f\u3001\u904e\u53bb\u306e\u7814\u7a76\u3067\u304a\u6b6f\u9ed2\u75d5\u8de1\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u305f\u5973\u6027\u500b\u4f53\u306b\u7531\u6765\u3059\u308b<em>M. oralis<\/em>\u304c\u3001\u3044\u305a\u308c\u3082\u540c\u4e00\u30af\u30ec\u30fc\u30c9\u306b\u542b\u307e\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u672c\u6210\u679c\u306f\u3001\u6b6f\u77f3\u306b\u6b8b\u3055\u308c\u305f\u3054\u304f\u5fae\u91cf\u306aDNA\u304c\u3001\u904e\u53bb\u306e\u4eba\u3005\u306e\u98df\u751f\u6d3b\u3001\u5730\u57df\u6027\u3001\u6587\u5316\u7fd2\u6163\u3001\u3055\u3089\u306b\u306f\u65e5\u672c\u5217\u5cf6\u306b\u304a\u3051\u308b\u4eba\u3068\u5fae\u751f\u7269\u306e\u95a2\u308f\u308a\u3092\u691c\u8a0e\u3059\u308b\u305f\u3081\u306e\u65b0\u305f\u306a\u624b\u304c\u304b\u308a\u3068\u306a\u308b\u3053\u3068\u3092\u793a\u3059\u3082\u306e\u3067\u3059\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u3053\u306e\u7814\u7a76\u6210\u679c\u306f2026\u5e746\u67088\u65e5\u306b\u96d1\u8a8c\u300cScientific Reports\u300d\u306b\u767a\u8868\u3055\u308c\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 12pt;\"><strong>\u25c6 \u767a\u8868\u8005\u540d<br \/>\n<\/strong>\u6817\u5c71 \u4f51\u57fa\uff08\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7cfb\u7814\u7a76\u79d1\u751f\u7269\u79d1\u5b66\u5c02\u653b\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u6c34\u91ce \u6587\u6708\uff08\u6771\u90a6\u5927\u5b66\u533b\u5b66\u90e8\u6cd5\u533b\u5b66\u8b1b\u5ea7\u3000\u51c6\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u5c71\u7530 \u5b5d\uff08\u6771\u90a6\u5927\u5b66\u533b\u5b66\u90e8\u6cd5\u533b\u5b66\u8b1b\u5ea7\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u718a\u8c37 \u771f\u5f66\uff08\u8fb2\u696d\u30fb\u98df\u54c1\u7523\u696d\u6280\u8853\u7dcf\u5408\u7814\u7a76\u6a5f\u69cb\u9ad8\u5ea6\u5206\u6790\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u3000\u4e3b\u4efb\u7814\u7a76\u54e1\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u7530\u4e2d \u771f\u751f\uff08\u7814\u7a76\u5f53\u6642\uff1a\u56fd\u969b\u533b\u7642\u798f\u7949\u5927\u5b66\u30b2\u30ce\u30e0\u533b\u5b66\u7814\u7a76\u6240\u3001<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u73fe\uff1a\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7cfb\u7814\u7a76\u79d1\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u4e2d \u4f0a\u6d25\u7f8e\uff08\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7cfb\u7814\u7a76\u79d1\u751f\u7269\u79d1\u5b66\u5c02\u653b\u3000\u7279\u4efb\u52a9\u6559\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u5e73\u7530 \u548c\u660e\uff08\u8056\u30de\u30ea\u30a2\u30f3\u30ca\u533b\u79d1\u5927\u5b66\u89e3\u5256\u5b66\u8b1b\u5ea7\u3000\u540d\u8a89\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u6c34\u5d8b \u5d07\u4e00\u90ce\uff08\u8056\u30de\u30ea\u30a2\u30f3\u30ca\u533b\u79d1\u5927\u5b66\u89e3\u5256\u5b66\u8b1b\u5ea7\u3000\u4e3b\u4efb\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u7c73\u5143 \u53f2\u7e54\uff08\u4e5d\u5dde\u5927\u5b66\u7dcf\u5408\u7814\u7a76\u535a\u7269\u9928\u3000\u51c6\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u821f\u6a4b \u4eac\u5b50\uff08\u4e5d\u5dde\u5927\u5b66\u5927\u5b66\u9662\u6bd4\u8f03\u793e\u4f1a\u6587\u5316\u7814\u7a76\u9662\u3000\u51c6\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u702c\u53e3 \u5178\u5b50\uff08\u4e5d\u5dde\u5927\u5b66\u5927\u5b66\u9662\u6bd4\u8f03\u793e\u4f1a\u6587\u5316\u7814\u7a76\u9662\u3000\u7279\u4efb\u7814\u7a76\u8005\uff0f<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u30e2\u30f3\u30bf\u30ca\u5927\u5b66\u30df\u30ba\u30fc\u30e9\u6821\u4eba\u985e\u5b66\u90e8\u3000Affiliate Professor\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u5742\u4e0a \u548c\u5f18\uff08\u56fd\u7acb\u79d1\u5b66\u535a\u7269\u9928\u751f\u547d\u53f2\u7814\u7a76\u90e8\u4eba\u985e\u53f2\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u3000\u30b0\u30eb\u30fc\u30d7\u9577\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u91d1\u6fa4 \u82f1\u4f5c\uff08\u65e5\u672c\u5927\u5b66\u677e\u6238\u6b6f\u5b66\u90e8\u3000\u540d\u8a89\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u677e\u4e0b \u771f\u5b9f\uff08\u571f\u4e95\u30f6\u6d5c\u907a\u8de1\u30fb\u4eba\u985e\u5b66\u30df\u30e5\u30fc\u30b8\u30a2\u30e0\u3000\u5b66\u82b8\u54e1\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u677e\u4e0b \u5b5d\u5e78\uff08\u571f\u4e95\u30f6\u6d5c\u907a\u8de1\u30fb\u4eba\u985e\u5b66\u30df\u30e5\u30fc\u30b8\u30a2\u30e0\u3000\u9928\u9577\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u4f50\u5b97 \u4e9c\u8863\u5b50\uff08\u65b0\u6f5f\u533b\u7642\u798f\u7949\u5927\u5b66\u81ea\u7136\u4eba\u985e\u5b66\u7814\u7a76\u6240\u3000\u8b1b\u5e2b\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u5948\u826f \u8cb4\u53f2\uff08\u65b0\u6f5f\u533b\u7642\u798f\u7949\u5927\u5b66\u81ea\u7136\u4eba\u985e\u5b66\u7814\u7a76\u6240 \u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u6fa4\u6d66 \u4eae\u5e73\uff08\u938c\u5009\u5973\u5b50\u5927\u5b66\u6559\u80b2\u5b66\u90e8\u3000\u8b1b\u5e2b\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u7247\u6850 \u5343\u4e9c\u7d00\uff08\u7814\u7a76\u5f53\u6642\uff1a\u6c96\u7e04\u770c\u7acb\u57cb\u8535\u6587\u5316\u8ca1\u30bb\u30f3\u30bf\u30fc\u3001\u73fe\uff1a\u6c96\u7e04\u770c\u6559\u80b2\u5e81\u6587\u5316\u8ca1\u8ab2\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u524d\u5ddd \u77e5\u6a39\uff08\u65b0\u6f5f\u5927\u5b66\u5927\u5b66\u9662\u533b\u6b6f\u4fdd\u5065\u5b66\u7814\u7a76\u79d1\u9ad8\u5ea6\u53e3\u8154\u6a5f\u80fd\u6559\u80b2\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\uff0f<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u7814\u7a76\u7d71\u62ec\u6a5f\u69cb\u3000\u7814\u7a76\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u9ed2\u5d0e \u4e45\u4ec1\u5f66\uff08\u6771\u90a6\u5927\u5b66\u533b\u5b66\u90e8\u6cd5\u533b\u5b66\u8b1b\u5ea7\u3000\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u6589\u85e4 \u4e45\u5b50\uff08\u6771\u4eac\u79d1\u5b66\u5927\u5b66\u5927\u5b66\u9662\u533b\u6b6f\u5b66\u7dcf\u5408\u7814\u7a76\u79d1\u6cd5\u6b6f\u5b66\u5206\u91ce\u3000\u51c6\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u4e26\u6728 \u4fee\u53f8\uff08\u6771\u4eac\u79d1\u5b66\u5927\u5b66\u5927\u5b66\u9662\u533b\u6b6f\u5b66\u7dcf\u5408\u7814\u7a76\u79d1\u6cd5\u6b6f\u5b66\u5206\u91ce\u3000\u7279\u4efb\u52a9\u6559\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u690d\u7530 \u4fe1\u592a\u90ce\uff08\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7cfb\u7814\u7a76\u79d1\u3000\u540d\u8a89\u6559\u6388\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u5927\u6a4b \u9806\uff08\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7cfb\u7814\u7a76\u79d1\u751f\u7269\u79d1\u5b66\u5c02\u653b\u3000\u6559\u6388\uff09<\/span><\/p>\n<p><span style=\"font-size: 12pt;\"><strong>\u25c6 \u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8<br \/>\n<\/strong>\u25cf \u6b6f\u77f3DNA\u304b\u3089\u904e\u53bb\u306e\u65e5\u672c\u5217\u5cf6\u4eba\u306e\u53e3\u8154\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u3092\u5fa9\u5143\u3057\u3001\u6c5f\u6238\u6642\u4ee3\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u53e4\u4eba\u9aa8\u306e\u6b6f\u77f3\u3092\u89e3\u6790\u3059\u308b\u3053\u3068\u3067\u3001\u904e\u53bb\u306e\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u7279\u5fb4\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u25cf \u53e4\u4eba\u9aa8\u7531\u6765\u6b6f\u77f3\u3068\u73fe\u4ee3\u6b6f\u77f3\u3067\u7570\u306a\u308b\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u7279\u5fb4\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u53e4\u4eba\u9aa8\u7531\u6765\u306e\u6b6f\u77f3\u3067\u306f\u73fe\u4ee3\u6b6f\u77f3\u3068\u306f\u7570\u306a\u308b\u5fae\u751f\u7269\u69cb\u6210\u304c\u898b\u3089\u308c\u3001\u5730\u57df\u5dee\u3084\u6642\u4ee3\u306b\u3088\u308b\u7d30\u83cc\u7cfb\u7d71\u306e\u9055\u3044\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u25cf \u304a\u6b6f\u9ed2\u75d5\u8de1\u3068\u6b6f\u5468\u75c5\u95a2\u9023\u53e4\u7d30\u83cc\u306e\u7cfb\u7d71\u306b\u7740\u76ee\u3057\u307e\u3057\u305f\u3002\u6b6f\u5468\u75c5\u95a2\u9023\u53e4\u7d30\u83cc&nbsp;<em>M. oralis<\/em>&nbsp;\u306f\u3001\u907a\u4f1d\u7684\u306b\u30af\u30ec\u30fc\u30c9A\u3068\u30af\u30ec\u30fc\u30c9B\u306e2\u3064\u306b\u5927\u304d\u304f\u5206\u304b\u308c\u3001\u304a\u6b6f\u9ed2\u75d5\u8de1\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u305f\u5973\u6027\u500b\u4f53\u304b\u3089\u691c\u51fa\u3055\u308c\u305f&nbsp;<em>M. oralis<\/em>&nbsp;\u306f\u3044\u305a\u308c\u3082\u30af\u30ec\u30fc\u30c9B\u306b\u5206\u985e\u3055\u308c\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/span><\/p>\n<p><span style=\"font-size: 12pt;\">\u25c6&nbsp;&nbsp;<strong>\u767a\u8868\u6982\u8981<br \/>\n<\/strong>\u6771\u90a6\u5927\u5b66\u533b\u5b66\u90e8\u6cd5\u533b\u5b66\u8b1b\u5ea7\u306e\u6c34\u91ce\u6587\u6708\u51c6\u6559\u6388\u3001\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7cfb\u7814\u7a76\u79d1\u306e\u6817\u5c71\u4f51\u57fa\u5927\u5b66\u9662\u751f\u3001\u690d\u7530\u4fe1\u592a\u90ce\u540d\u8a89\u6559\u6388\u3001\u5927\u6a4b\u9806\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6c5f\u6238\u6642\u4ee3\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u65e5\u672c\u5217\u5cf6\u53e4\u4eba\u9aa8\u306e\u6b6f\u77f3\u306b\u6b8b\u3055\u308c\u305fDNA\u3092\u89e3\u6790\u3057\u3001\u904e\u53bb\u306e\u53e3\u8154\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u306e\u7279\u5fb4\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u53e4\u4eba\u9aa8\u306e\u6b6f\u77f3\u306b\u306f\u3001\u5f53\u6642\u306e\u53e3\u8154\u5185\u5fae\u751f\u7269\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u3055\u307e\u3056\u307e\u306aDNA\u304c\u6b8b\u3055\u308c\u3066\u304a\u308a\u3001\u904e\u53bb\u306e\u751f\u6d3b\u3084\u5065\u5eb7\u72b6\u614b\u3092\u77e5\u308b\u624b\u304c\u304b\u308a\u3068\u306a\u308a\u307e\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u53e4\u4eba\u9aa8\u7531\u6765\u6b6f\u77f3\u3068\u73fe\u4ee3\u6b6f\u77f3\u306b\u542b\u307e\u308c\u308b\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u9055\u3044\u3001\u5730\u57df\u5dee\u3001\u7e04\u6587\u6642\u4ee3\u3068\u6c5f\u6238\u6642\u4ee3\u306e\u9593\u306b\u307f\u3089\u308c\u308b\u4e00\u90e8\u306e\u7d30\u83cc\u7cfb\u7d71\u306e\u9055\u3044\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u6b6f\u5468\u75c5\u95a2\u9023\u53e4\u7d30\u83cc<em>M. oralis<\/em>\u306e\u7cfb\u7d71\u89e3\u6790\u306b\u3088\u308a\u3001\u304a\u6b6f\u9ed2\u75d5\u8de1\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u305f\u5973\u6027\u500b\u4f53\u306b\u7531\u6765\u3059\u308b<em>M. oralis<\/em>\u306f\u3001\u3044\u305a\u308c\u3082\u540c\u4e00\u30af\u30ec\u30fc\u30c9\u306b\u542b\u307e\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u672c\u6210\u679c\u306f\u3001\u6b6f\u77f3\u4e2d\u306e\u5fae\u751f\u7269DNA\u304c\u3001\u904e\u53bb\u306e\u4eba\u3005\u306e\u98df\u751f\u6d3b\u3001\u5730\u57df\u6027\u3001\u6587\u5316\u7fd2\u6163\u3001\u4eba\u3068\u5fae\u751f\u7269\u306e\u95a2\u4fc2\u306e\u6b74\u53f2\u3092\u691c\u8a0e\u3059\u308b\u65b0\u305f\u306a\u624b\u304c\u304b\u308a\u3068\u306a\u308b\u3053\u3068\u3092\u793a\u3059\u3082\u306e\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 12pt;\">\u25c6&nbsp;&nbsp;<strong>\u767a\u8868\u5185\u5bb9<br \/>\n<\/strong>\u30d2\u30c8\u306e\u4f53\u306b\u306f\u3001\u53e3\u8154\u3001\u8178\u3001\u76ae\u819a\u306a\u3069\u306b\u591a\u69d8\u306a\u5fae\u751f\u7269\u304c\u5171\u751f\u3057\u3066\u304a\u308a\u3001\u305d\u306e\u96c6\u307e\u308a\u306f\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u3068\u547c\u3070\u308c\u3066\u3044\u307e\u3059\u3002\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u306f\u3001\u98df\u751f\u6d3b\u3001\u885b\u751f\u74b0\u5883\u3001\u751f\u6d3b\u69d8\u5f0f\u3001\u85ac\u5264\u4f7f\u7528\u306a\u3069\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3066\u5909\u5316\u3057\u3001\u5065\u5eb7\u72b6\u614b\u3068\u3082\u95a2\u308f\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u53e3\u8154\u5185\u306e\u5fae\u751f\u7269\u306f\u3001\u866b\u6b6f\u3084\u6b6f\u5468\u75c5\u306a\u3069\u306e\u53e3\u8154\u75be\u60a3\u3068\u95a2\u4fc2\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u751f\u6d3b\u74b0\u5883\u3084\u98df\u6587\u5316\u3092\u53cd\u6620\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u65e5\u672c\u5217\u5cf6\u306e\u904e\u53bb\u306e\u96c6\u56e3\u306b\u304a\u3044\u3066\u3001\u53e3\u8154\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u304c\u6642\u4ee3\u3084\u5730\u57df\u3001\u6587\u5316\u7fd2\u6163\u306b\u3088\u3063\u3066\u3069\u306e\u3088\u3046\u306b\u5909\u5316\u3057\u3066\u304d\u305f\u306e\u304b\u306f\u3001\u5341\u5206\u306b\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u8fd1\u5e74\u3001\u53e4\u4eba\u9aa8\u306e\u6b6f\u306b\u4ed8\u7740\u3057\u305f\u6b6f\u77f3\u304b\u3089\u3001\u904e\u53bb\u306e\u53e3\u8154\u5185\u5fae\u751f\u7269\u3092\u8abf\u3079\u308b\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u6b6f\u77f3\u306f\u3001\u6b6f\u57a2\u304c\u77f3\u7070\u5316\u3057\u3066\u786c\u304f\u306a\u3063\u305f\u3082\u306e\u3067\u3001\u5f53\u6642\u306e\u53e3\u8154\u5185\u5fae\u751f\u7269\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u3055\u307e\u3056\u307e\u306aDNA\u304c\u6b8b\u3055\u308c\u3066\u3044\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u6b6f\u77f3\u4e2d\u306eDNA\u306f\u3001\u904e\u53bb\u306e\u751f\u6d3b\u3084\u5065\u5eb7\u72b6\u614b\u3092\u77e5\u308b\u305f\u3081\u306e\u6709\u7528\u306a\u60c5\u5831\u6e90\u3068\u306a\u308a\u307e\u3059\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u672c\u7814\u7a76\u3067\u306f\u3001\u6771\u4eac\u90fd\u3001\u57fc\u7389\u770c\u3001\u5c71\u68a8\u770c\u3001\u798f\u5ca1\u770c\u3001\u6c96\u7e04\u770c\u306b\u6240\u5728\u3059\u308b\u907a\u8de1\u30fb\u5893\u5730\u306a\u3069\u304b\u3089\u51fa\u571f\u3057\u305f\u3001\u4e3b\u306b\u8fd1\u4e16\u306e\u53e4\u4eba\u9aa8\u7531\u6765\u6b6f\u77f3\u8a66\u6599\u306b\u52a0\u3048\u3001\u65b0\u6f5f\u770c\u306e\u73fe\u4ee3\u6b6f\u77f3\u8a66\u6599\u3092\u65b0\u305f\u306b\u89e3\u6790\u3057\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u5148\u884c\u7814\u7a76\u3067\u5831\u544a\u3055\u308c\u305f\u7e04\u6587\u6642\u4ee3\u304a\u3088\u3073\u6c5f\u6238\u6642\u4ee3\u306e\u6b6f\u77f3\u30c7\u30fc\u30bf\u3082\u52a0\u3048\u3001\u53e4\u4eba\u9aa8\u7531\u6765\u6b6f\u77f3\u304a\u3088\u3073\u73fe\u4ee3\u6b6f\u77f3\u4e2d\u306e\u5fae\u751f\u7269\u306e\u69cb\u6210\u3001\u6a5f\u80fd\u3001\u7cfb\u7d71\u95a2\u4fc2\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002\u53e4\u4eba\u9aa8\u7531\u6765\u306e\u6b6f\u77f3\u8a66\u6599\u3067\u306f\u571f\u58cc\u7531\u6765\u306e\u5fae\u751f\u7269\u306b\u3088\u308b\u6c5a\u67d3\u304c\u554f\u984c\u3068\u306a\u308b\u305f\u3081\u3001\u65e2\u77e5\u306e\u53e3\u8154\u5185\u5fae\u751f\u7269\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u7528\u3044\u3066\u3001\u53e3\u8154\u7531\u6765\u3068\u8003\u3048\u3089\u308c\u308b\u5fae\u751f\u7269\u306b\u7d5e\u3063\u3066\u89e3\u6790\u3057\u307e\u3057\u305f\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u89e3\u6790\u306e\u7d50\u679c\u3001\u53e4\u4ee3\u6b6f\u77f3\u306b\u542b\u307e\u308c\u308b\u53e3\u8154\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u306f\u3001\u73fe\u4ee3\u6b6f\u77f3\u3068\u306f\u7570\u306a\u308b\u69cb\u6210\u3092\u793a\u3057\u307e\u3057\u305f\uff08\u56f31\uff09\u3002\u7279\u306b\u3001\u6b6f\u5468\u75c5\u3068\u306e\u95a2\u9023\u304c\u77e5\u3089\u308c\u308b\u53e4\u7d30\u83cc<em>M. oralis<\/em>\u306f\u3001\u53e4\u4ee3\u6b6f\u77f3\u3067\u591a\u304f\u691c\u51fa\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u672c\u5dde\u30fb\u4e5d\u5dde\u5730\u57df\u3068\u6c96\u7e04\u5730\u57df\u306e\u9593\u3067\u5fae\u751f\u7269\u69cb\u6210\u306b\u9055\u3044\u304c\u898b\u3089\u308c\u3001\u5730\u57df\u3054\u3068\u306e\u751f\u6d3b\u74b0\u5883\u3084\u98df\u7fd2\u6163\u304c\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u69cb\u6210\u306b\u95a2\u308f\u3063\u3066\u3044\u305f\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u4e00\u65b9\u3067\u3001\u7e04\u6587\u6642\u4ee3\u3068\u6c5f\u6238\u6642\u4ee3\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u8fd1\u4e16\u306e\u8a66\u6599\u3092\u6bd4\u8f03\u3057\u305f\u3068\u3053\u308d\u3001\u8907\u6570\u306e\u7d30\u83cc\u3067\u6642\u4ee3\u3054\u3068\u306b\u7570\u306a\u308b\u7cfb\u7d71\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u65e5\u672c\u5217\u5cf6\u306b\u304a\u3051\u308b\u4eba\u306e\u79fb\u52d5\u3001\u8fb2\u8015\u306e\u5c0e\u5165\u3001\u98df\u751f\u6d3b\u306e\u5909\u5316\u306a\u3069\u304c\u3001\u30d2\u30c8\u3060\u3051\u3067\u306a\u304f\u3001\u30d2\u30c8\u3068\u3068\u3082\u306b\u751f\u304d\u3066\u304d\u305f\u5fae\u751f\u7269\u306e\u591a\u69d8\u6027\u306b\u3082\u95a2\u308f\u3063\u3066\u3044\u305f\u53ef\u80fd\u6027\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u52a0\u3048\u3066\u3001\u6b6f\u5468\u75c5\u95a2\u9023\u53e4\u7d30\u83cc&nbsp;<em>M. oralis<\/em>&nbsp;\u306e\u7cfb\u7d71\u5206\u5e03\u306b\u7740\u76ee\u3057\u3001\u8fd1\u4e16\u3001\u7279\u306b\u6c5f\u6238\u6642\u4ee3\u306b\u5e83\u304f\u898b\u3089\u308c\u305f\u6587\u5316\u7fd2\u6163\u3067\u3042\u308b\u300c\u304a\u6b6f\u9ed2\u300d\u3068\u306e\u95a2\u4fc2\u3092\u8abf\u3079\u307e\u3057\u305f\u3002\u89e3\u6790\u306e\u7d50\u679c\u3001\u53e4\u4ee3\u6b6f\u77f3\u306b\u7531\u6765\u3059\u308b&nbsp;<em>M. oralis&nbsp;<\/em>\u306f\u5927\u304d\u304f\u30af\u30ec\u30fc\u30c9A\u3068\u30af\u30ec\u30fc\u30c9B\u306e2\u3064\u306e\u7cfb\u7d71\u306b\u5206\u304b\u308c\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u904e\u53bb\u306e\u7814\u7a76\u3067\u304a\u6b6f\u9ed2\u306e\u75d5\u8de1\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u305f\u5973\u6027\u500b\u4f53\u306b\u7531\u6765\u3059\u308b<em>M. oralis<\/em>\u306f\u3001\u3044\u305a\u308c\u3082\u30af\u30ec\u30fc\u30c9B\u306b\u542b\u307e\u308c\u3066\u3044\u307e\u3057\u305f\uff08\u56f32\uff09\u3002\u3053\u306e\u7d50\u679c\u306f\u3001\u304a\u6b6f\u9ed2\u3068\u3044\u3046\u6587\u5316\u7fd2\u6163\u3068\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u7cfb\u7d71\u5206\u5e03\u3068\u306e\u95a2\u4fc2\u3092\u691c\u8a0e\u3059\u308b\u624b\u304c\u304b\u308a\u3068\u306a\u308a\u307e\u3059\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u307e\u305f\u3001<em>M. oralis<\/em>&nbsp;\u306e\u907a\u4f1d\u5b50\u3092\u6bd4\u8f03\u3057\u305f\u3068\u3053\u308d\u3001\u9244\u5229\u7528\u306b\u95a2\u308f\u308b\u4ee3\u8b1d\u95a2\u9023\u907a\u4f1d\u5b50\u306b\u7cfb\u7d71\u7279\u7570\u7684\u306a\u5909\u7570\u304c\u898b\u51fa\u3055\u308c\u307e\u3057\u305f\u3002\u304a\u6b6f\u9ed2\u3067\u306f\u9244\u3092\u542b\u3080\u6210\u5206\u3084\u690d\u7269\u7531\u6765\u6210\u5206\u304c\u7528\u3044\u3089\u308c\u3066\u3044\u305f\u3053\u3068\u304b\u3089\u3001\u3053\u3046\u3057\u305f\u53e3\u8154\u5185\u74b0\u5883\u306e\u9055\u3044\u304c\u7279\u5b9a\u306e\u5fae\u751f\u7269\u7cfb\u7d71\u306e\u5206\u5e03\u306b\u95a2\u308f\u3063\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u305d\u306e\u56e0\u679c\u95a2\u4fc2\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u306b\u306f\u3001\u4eca\u5f8c\u3001\u304a\u6b6f\u9ed2\u75d5\u8de1\u306e\u4f53\u7cfb\u7684\u306a\u8a18\u9332\u3084\u6b6f\u77f3\u4e2d\u306e\u5316\u5b66\u6210\u5206\u5206\u6790\u3092\u542b\u3080\u8ffd\u52a0\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u672c\u6210\u679c\u306f\u3001\u6b6f\u77f3\u306b\u6b8b\u3055\u308c\u305f\u5fae\u751f\u7269DNA\u304c\u3001\u904e\u53bb\u306e\u4eba\u3005\u306e\u5065\u5eb7\u72b6\u614b\u3060\u3051\u3067\u306a\u304f\u3001\u98df\u751f\u6d3b\u3001\u5730\u57df\u6027\u3001\u6587\u5316\u7fd2\u6163\u3001\u4eba\u3068\u5fae\u751f\u7269\u306e\u95a2\u4fc2\u306e\u6b74\u53f2\u3092\u691c\u8a0e\u3059\u308b\u305f\u3081\u306e\u65b0\u3057\u3044\u7814\u7a76\u6750\u6599\u3068\u306a\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u4eca\u5f8c\u3001\u3088\u308a\u591a\u304f\u306e\u6642\u4ee3\u30fb\u5730\u57df\u306e\u8a66\u6599\u89e3\u6790\u3084\u3001\u6b6f\u77f3\u306b\u6b8b\u308b\u5316\u5b66\u6210\u5206\u3001\u8003\u53e4\u5b66\u7684\u60c5\u5831\u3068\u306e\u7d71\u5408\u306b\u3088\u308a\u3001\u65e5\u672c\u5217\u5cf6\u306b\u66ae\u3089\u3057\u305f\u4eba\u3005\u306e\u751f\u6d3b\u53f2\u3084\u5fae\u751f\u7269\u3068\u306e\u95a2\u4fc2\u3092\u3001\u3088\u308a\u8a73\u7d30\u306b\u5fa9\u5143\u3067\u304d\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 12pt;\">\u25c6&nbsp;&nbsp;<strong>\u767a\u8868\u96d1\u8a8c<br \/>\n<\/strong>\u96d1\u8a8c\u540d\uff1a\u300cScientific Reports\u300d\uff082026\u5e746\u67088\u65e5\u516c\u958b\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb\uff1aInsights into demographic and cultural influences on the oral microbiome from historical Japanese dental calculus<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u8457\u8005\uff1aYuki Kuriyama, Fuzuki Mizuno*, Takashi Yamada, Masahiko Kumagai, Masaki Tanaka, Izumi Naka, Kazuaki Hirata, Soichiro Mizushima, Shiori Yonemoto, Kyoko Funahashi, Noriko Seguchi, Kazuhiro Sakaue, Eisaku Kanazawa, Masami Matsushita, Takayuki Matsushita, Aiko Saso, Takashi Nara, Ryohei Sawaura, Chiaki Katagiri, Tomoki Maekawa, Kunihiko Kurosaki, Hisako Saitoh, Shuuji Namiki, Shintaroh Ueda*, Jun Ohashi*\uff08* \u8cac\u4efb\u8457\u8005\uff09<\/span><br \/>\n<span style=\"font-size: 12pt;\">DOI\u756a\u53f7\uff1a10.1038\/s41598-026-55286-2<\/span><\/p>\n<p><span style=\"font-size: 12pt;\"><strong>\u25c6 \u7528\u8a9e\u89e3\u8aac<br \/>\n<\/strong>\uff08\u6ce81\uff09\u53e3\u8154\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u53e3\u306e\u4e2d\u306b\u5b58\u5728\u3059\u308b\u7d30\u83cc\u3001\u53e4\u7d30\u83cc\u3001\u771f\u83cc\u3001\u30a6\u30a4\u30eb\u30b9\u306a\u3069\u306e\u5fae\u751f\u7269\u306e\u96c6\u307e\u308a\u3001\u307e\u305f\u306f\u305d\u308c\u3089\u306e\u907a\u4f1d\u60c5\u5831\u5168\u4f53\u3092\u6307\u3057\u307e\u3059\u3002\u98df\u751f\u6d3b\u3084\u885b\u751f\u72b6\u614b\u3001\u751f\u6d3b\u74b0\u5883\u3001\u75be\u60a3\u306a\u3069\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3066\u5909\u5316\u3057\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 12pt;\">\uff08\u6ce82\uff09<em>Methanobrevibacter oralis\uff08M. oralis\uff09<br \/>\n<\/em>\u30d2\u30c8\u306e\u53e3\u8154\u5185\u306b\u5b58\u5728\u3059\u308b\u53e4\u7d30\u83cc\u306e\u4e00\u7a2e\u3067\u3001\u6b6f\u5468\u75c5\u3068\u306e\u95a2\u9023\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u6c5f\u6238\u6642\u4ee3\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u8fd1\u4e16\u306e\u6b6f\u77f3\u8a66\u6599\u304b\u3089\u591a\u304f\u691c\u51fa\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/p>\n<p><span style=\"font-size: 12pt;\">\u25c6&nbsp;&nbsp;<strong>\u6dfb\u4ed8\u8cc7\u6599<\/strong><\/span><\/p>\n<div class=\"pr-img\">\n<figure class=\"pr-img__item--large\"><span style=\"font-size: 12pt;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"https:\/\/prcdn.freetls.fastly.net\/release_image\/32951\/2057\/32951-2057-0ecf14820820d851cdd817644dc96c0a-708x337.png?width=1950&amp;height=1350&amp;quality=85&amp;format=jpeg&amp;auto=webp&amp;fit=bounds&amp;bg-color=fff\" alt=\"\u65b0\u305f\u306b\u89e3\u6790\u3057\u305f\u6b6f\u77f3\u8a66\u6599\u3068\u5148\u884c\u7814\u7a76\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3066\u3001\u53e4\u4ee3\u304a\u3088\u3073\u73fe\u4ee3\u306e\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u69cb\u6210\u3092\u6bd4\u8f03\u3057\u305f\u56f3\" width=\"708\" height=\"337\"><\/span><span style=\"font-size: 12pt;\">\u56f31\uff0e\u6b6f\u77f3DNA\u304b\u3089\u8aad\u307f\u89e3\u304f\u3001\u904e\u53bb\u306e\u53e3\u8154\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0 \u65b0\u305f\u306b\u89e3\u6790\u3057\u305f\u6b6f\u77f3\u8a66\u6599\u3068\u5148\u884c\u7814\u7a76\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3066\u3001\u53e4\u4ee3\u304a\u3088\u3073\u73fe\u4ee3\u306e\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u69cb\u6210\u3092\u6bd4\u8f03\u3057\u305f\u56f3\u3002<\/span><\/figure>\n<\/div>\n<div class=\"pr-img\">\n<figure class=\"pr-img__item--large\"><span style=\"font-size: 12pt;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"https:\/\/prcdn.freetls.fastly.net\/release_image\/32951\/2057\/32951-2057-4637e678e9aa3ad3873ccef58ed838f1-735x475.png?width=1950&amp;height=1350&amp;quality=85&amp;format=jpeg&amp;auto=webp&amp;fit=bounds&amp;bg-color=fff\" alt=\"\u304a\u6b6f\u9ed2\u75d5\u8de1\u3068\u6b6f\u5468\u75c5\u95a2\u9023\u53e4\u7d30\u83cc M. oralis \u306e\u7cfb\u7d71\u306b\u95a2\u3059\u308b\u56f3\" width=\"735\" height=\"475\"><\/span><span style=\"font-size: 12pt;\">\u56f32\uff0e\u304a\u6b6f\u9ed2\u75d5\u8de1\u3068\u6b6f\u5468\u75c5\u95a2\u9023\u53e4\u7d30\u83cc M. oralis \u306e\u7cfb\u7d71 \u904e\u53bb\u306e\u7814\u7a76\u3067\u304a\u6b6f\u9ed2\u75d5\u8de1\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u305f\u5973\u6027\u500b\u4f53\u306f\u3001M. oralis \u306e\u30af\u30ec\u30fc\u30c9B\u306b\u542b\u307e\u308c\u3066\u3044\u305f\u3002<\/span><\/figure>\n<\/div>\n<p><span style=\"font-size: 12pt;\">\u25c6&nbsp;&nbsp;<strong>\u304a\u554f\u3044\u5408\u308f\u305b\u5148<br \/>\n<\/strong><strong>\u3010\u7814\u7a76\u306b\u95a2\u3059\u308b\u304a\u554f\u3044\u5408\u308f\u305b\u3011<br \/>\n<\/strong>\u6771\u90a6\u5927\u5b66\u533b\u5b66\u90e8\u6cd5\u533b\u5b66\u8b1b\u5ea7<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u51c6\u6559\u6388\u3000\u6c34\u91ce \u6587\u6708<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u3012143-8540\u3000\u6771\u4eac\u90fd\u5927\u7530\u533a\u5927\u68ee\u897f5-21-16<\/span><br \/>\n<span style=\"font-size: 12pt;\">E-mail: fuzuki.mizuno@med.toho-u.ac.jp<\/span><\/p>\n<p><span style=\"font-size: 12pt;\">\u6771\u4eac\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7cfb\u7814\u7a76\u79d1\u751f\u7269\u79d1\u5b66\u5c02\u653b<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u6559\u6388\u3000\u5927\u6a4b \u9806<\/span><br \/>\n<span style=\"font-size: 12pt;\">\u3012113-0033\u3000\u6771\u4eac\u90fd\u6587\u4eac\u533a\u672c\u90f77-3-1<\/span><br \/>\n<span style=\"font-size: 12pt;\">E-mail: jun_ohashi@bs.s.u-tokyo.ac.jp<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6771\u90a6\u5927\u5b66\u3001\u6771\u4eac\u5927\u5b66\u3001\u8fb2\u696d\u30fb\u98df\u54c1\u7523\u696d\u6280\u8853\u7dcf\u5408\u7814\u7a76\u6a5f\u69cb\u3001\u56fd\u969b\u533b\u7642\u798f\u7949\u5927\u5b66\u3001\u8056\u30de\u30ea\u30a2\u30f3\u30ca\u533b\u79d1\u5927\u5b66\u3001\u4e5d\u5dde\u5927\u5b66\u3001\u56fd\u7acb\u79d1\u5b66\u535a\u7269\u9928\u3001\u65e5\u672c\u5927\u5b66\u3001\u571f\u4e95\u30f6\u6d5c\u907a\u8de1\u30fb\u4eba\u985e\u5b66\u30df\u30e5\u30fc\u30b8\u30a2\u30e0\u3001\u65b0\u6f5f\u533b\u7642\u798f\u7949\u5927\u5b66\u3001\u938c\u5009\u5973\u5b50\u5927\u5b66\u3001\u6c96\u7e04\u770c\u7acb\u57cb\u8535\u6587\u5316\u8ca1\u30bb\u30f3\u30bf\u30fc &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.nsg.gr.jp\/blog\/nuhw_ancient-dental-calculus_202606\/\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;\u6b6f\u77f3DNA\u304b\u3089\u8aad\u307f\u89e3\u304f\u3001\u904e\u53bb\u306e\u65e5\u672c\u4eba\u3068\u53e3\u8154\u5185\u5fae\u751f\u7269\u306e\u95a2\u308f\u308a&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[40,41,49,178,180],"tags":[57,65,73],"class_list":["post-18743","post","type-post","status-publish","format-standard","hentry","category-cat-l-02","category-cat-l-02-01","category-sustaina","category-178","category-180","tag-57","tag-65","tag-73","fixedpage_taxonomy-hito","fixedpage_feed_taxonomy-hito"],"_links":{"self":[{"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/posts\/18743","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/comments?post=18743"}],"version-history":[{"count":2,"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/posts\/18743\/revisions"}],"predecessor-version":[{"id":18745,"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/posts\/18743\/revisions\/18745"}],"wp:attachment":[{"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/media?parent=18743"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/categories?post=18743"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nsg.gr.jp\/blog\/wp-json\/wp\/v2\/tags?post=18743"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}